陆春风-yb体育官方

作者:金飞     日期:2023-09-26   点击数:2912  

     师资介绍

陆春风,男,汉族,19892月,博士,副教授,硕士生导师

研究方向:中医药防治肝病 

基金项目:

1)    国家自然科学基金委员会,青年项目,81803606,川芎嗪通过sestrin2调控自噬介导的肝细胞程序性坏死防治酒精性肝病的机制研究,2019-012021-1221万元,结题,主持。

2)    江苏省高等学校自然科学研究项目,22kjb360015,基于uqcrc2介导自噬探究紫檀芪抑制酒精性肝细胞衰老的机制,2022-072024-063万元,在研,主持。

3)    南通市科学计划项目,ms12018051nrf2/hmgb1轴调控细胞程序性坏死在奥沙利铂致肝毒性中的作用及临床意义,2018-072020-0610万元,结题,主持。

代表性论文:

1)         ge t, shao y, bao x, xu w, lu c(通讯作者). cellular senescence in liver diseases: from mechanisms to therapies. int immunopharmacol. 2023 aug;121:110522.(二区)

2)         jiang y, zhou y, xu w, wang x, jin h, bao x, lu c(通讯作者). induction of sestrin2 by pterostilbene suppresses ethanol-triggered hepatocyte senescence by degrading ccn1 via p62-dependent selective autophagy. cell biol toxicol. 2023 jun;39(3):729-749.(二区)

3)         lu c(第一作者), jiang y, xu w, bao x. sestrin2: multifaceted functions, molecular basis, and its implications in liver diseases. cell death dis. 2023 feb 25;14(2):160.(一区)

4)         lu c(第一作者), ge t, shao y, cui w, li z, xu w, bao x. znf281 drives hepatocyte senescence in alcoholic liver disease by reducing hk2-stabilized pink1/parkin-mediated mitophagy. cell prolif. 2023 mar;56(3):e13378.(一区)

5)         zhou y, wu r, wang x, bao x, lu c(通讯作者). roles of necroptosis in alcoholic liver disease and hepatic pathogenesis. cell prolif. 2022 mar;55(3):e13193.(一区)

6)         zhou y, wu r, wang x, jiang y, xu w, shao y, yue c, shi w, jin h, ge t, bao x, lu c(通讯作者). activation of uqcrc2-dependent mitophagy by tetramethylpyrazine inhibits mlkl-mediated hepatocyte necroptosis in alcoholic liver disease. free radic biol med. 2022 feb 1;179:301-316.(一区)

7)         shao y, wang x, zhou y, jiang y, wu r, lu c(通讯作者). pterostilbene attenuates ripk3-dependent hepatocyte necroptosis in alcoholic liver disease via sirt2-mediated nfatc4 deacetylation. toxicology. 2021 sep;461:152923.(三区)

8)         wu r, wang x, shao y, jiang y, zhou y, lu c(通讯作者). nfatc4 mediates ethanol-triggered hepatocyte senescence. toxicol lett. 2021 oct 10;350:10-21.(三区)

9)         zhou y, jin h, wu y, chen l, bao x, lu c(通讯作者). gallic acid protects against ethanol-induced hepatocyte necroptosis via an nrf2-dependent mechanism. toxicol in vitro. 2019 jun;57:226-232.(三区)


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